Standard Therapies with blood-forming stem cells These are diseases for which transplants of blood-forming stem cells (Hematopoietic Stem Cell Transplants, GCSH) are a standard treatment. For some diseases they are the only therapy, and in other diseases they are only employed when front-line therapies have failed or the disease is Lire la suite

Can mesenchymal stem cells induce tolerance to cotransplanted human embryonic stem cells?

Can mesenchymal stem cells induce tolerance to cotransplanted human embryonic stem cells? Puymirat E1, Geha R, Tomescot A, Bellamy V, Larghero J, Trinquart L, Bruneval P, Desnos M, Hagège A, Pucéat M, Menasché P. Cellules souches mésenchymateuses (MSC) are reported to be immune privileged. We assessed whether their transplantation (Tx) Lire la suite

thérapie par cellules souches en Chine

Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial.

Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial. Cellules souches mésenchymateuses (MSC) are under evaluation as a therapy for ischemic cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; cependant, their safety and efficacy Lire la suite

cellules souches Espagne

Comparison of Mesenchymal Stem Cell Efficacy in Ischemic Versus Nonischemic Dilated Cardiomyopathy

Comparison of Mesenchymal Stem Cell Efficacy in Ischemic Versus Nonischemic Dilated Cardiomyopathy. Abstract BACKGROUND: Cardiomyopathie ischémique (ICM) and dilated cardiomyopathy (DCM) differ in histopathology and prognosis. Although transendocardial delivery of mesenchymal stem cells is safe and provides cardiovascular benefits in both, a comparison of mesenchymal stem cell efficacy in ICM Lire la suite

clinique de thérapie par cellules souches du cancer

Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial.

Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial.   Abstract BACKGROUND: The prevalence of type 2 diabète (DT2) is increasing worldwide and creating a significant burden on health systems, highlighting the need Lire la suite

back pain stem cell therapy in Ukraine

Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature

Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature The use of primary mesenchymal stem cells (MSC) is fraught with ageing-related shortfalls such as limited expansion and early senescence. Human induced pluripotent stem cells (iPSC) -derived MSCs (iMSCs) have been shown to be a useful clinically relevant source Lire la suite

thérapie par cellules souches en France

Comparative Characterization of Ischemia-Induced Brain Multipotent Stem Cells with Mesenchymal Stem Cells: Similarities and Differences

Comparative Characterization of Ischemia-Induced Brain Multipotent Stem Cells with Mesenchymal Stem Cells: Similarities and Differences mesenchymal stem cells (MSC) are multipotent stem cells localized to the perivascular regions of various organs, y compris la moelle osseuse (BM). While MSC transplantation represents a promising stem cell-based therapy for ischemic stroke, increasing evidence indicates Lire la suite

thérapie par cellules souches en Chine

Spaceflight Activates Protein Kinase C Alpha Signaling and Modifies the Developmental Stage of Human Neonatal Cardiovascular Progenitor Cells

Spaceflight Activates Protein Kinase C Alpha Signaling and Modifies the Developmental Stage of Human Neonatal Cardiovascular Progenitor Cells Spaceflight impacts cardiovascular function in astronauts; cependant, its impact on cardiac development and the stem cells that form the basis for cardiac repair is unknown. Accordingly, further research is needed to Lire la suite

thérapie par cellules souches Turquie

Identification of Multipotent Stem Cells in Human Brain Tissue Following Stroke

Identification of Multipotent Stem Cells in Human Brain Tissue Following Stroke Perivascular regions of the brain harbor multipotent stem cells. We previously demonstrated that brain pericytes near blood vessels also develop multipotency following experimental ischemia in mice and these ischemia-induced multipotent stem cells (iSCs) can contribute to neurogenesis. Cependant, il Lire la suite