干细胞治疗多发性硬化症 (多发性硬化症).
干细胞移植治疗国际试验的中期结果显示，其成功率比对照组高得多, 接受过药物治疗. 多发性硬化症是一种影响大脑的疾病, 脊髓, 和免疫系统, leading to a number of disabilities. 这 干细胞治疗 uses chemotherapy to wipe out a patient’s immune system and then “re-boots” it using stem cells from the patient’s blood and bone marrow that are unaffected by the disease.
Just over 100 people participated in the study in four cities: in Chicago, Sao Paolo, Sheffield (U.K.), and Uppsala in Sweden. They all had relapsing remitting MS, where periods of symptomatic “relapses” alternate with periods of remission. A year after the treatment, only one patient who received the 干细胞治疗 had relapsed, compared to 39 people in the control group.
In a follow-up an average of three years after treatment, 这 干细胞 had failed in 6% (3 的 52) of recipients while the drug treatment had failed in 60% (30 的 50). The results were released at the annual meeting of the European Society for Bone and Marrow Transplantation in Lisbon.
A neurologist at Royal Hallamshire Hospital in the U.K. told the BBC this was the best result he had seen “in any trial for multiple sclerosis,” though he included the caveat that the results were only preliminary.
This study is the largest of its kind, and it bolsters results from smaller trials that have also showed stem cell transplant to be effective.
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