Mesure de la longueur des télomères et thérapies anti-âge.

Chaque fois que les cellules se répliquent, telomeres shorten until they reach a point where the cells can no longer divide properly. Cells with such short telomeres usually become senescent or enter apoptosis, Et finalement mourir. Donc, telomere length is a crucial biomarker providing insight into understanding organismal aging.

Telomere lengths are frequently measured in biomedical research. Récemment, we developed a singleplex quantitative polymerase chain reaction (QPCR) assay for relative average telomere lengths, which uses far less DNA and requires much less time to perform than the traditional Southern blot method for measuring Terminal Restriction Fragment (TRF) lengths.

A new procedure can quickly and efficiently increase the length of human telomeres, the protective caps on the ends of chromosomes that are linked to aging and disease, according to scientists.