Enfermedad renal crónica (ERC) affects millions worldwide and is a leading cause of morbidity and mortality. While various treatment options exist, many patients progress to end-stage renal disease (ESRD), requiring dialysis or kidney transplantation. Terapia con células madre has emerged as a promising approach for CKD, offering the potential to repair damaged tissue and restore kidney function.
Terapia con células madre: A Promising Approach for Chronic Kidney Disease
Las células madre son células no especializadas que tienen la capacidad de diferenciarse en varios tipos de células.. In the context of CKD, stem cells can be used to replace damaged kidney cells and restore kidney function. Several types of stem cells have been investigated for CKD treatment, incluyendo células madre embrionarias, células madre pluripotentes inducidas (iPSC), y células madre mesenquimales (MSC). Each type of stem cell has its own advantages and disadvantages, and the optimal choice for CKD treatment depends on factors such as the stage of disease and the patient’s overall health.
Infection-Related Origins and Stem Cell Applications
Infections are a common cause of CKD, and they can lead to damage to the kidney’s filtering units (glomeruli) and tubules. This damage can result in scarring and a decline in kidney function. Terapia con células madre has shown promise in treating CKD caused by infection. Por ejemplo, MSCs have been shown to reduce inflammation and promote tissue repair in animal models of CKD caused by infection. Además, iPSCs have been used to generate kidney organoids, which can be used for drug screening and to study the pathogenesis of CKD.
Terapia con células madre holds great promise for the treatment of CKD, including cases caused by infection. While further research is needed to optimize stem cell delivery and to evaluate the long-term safety and efficacy of this approach, terapia con células madre has the potential to revolutionize the treatment of CKD and improve the lives of millions of patients worldwide.
