العلاج بالخلايا الجذعية

العلاج بالخلايا الجذعية في أوكرانيا

Issues of congenital heart disease

Issues of congenital heart disease Location: Kiev,Ukraine Start Date: 2012-09-23 End Date: 2012-09-24 Conditions of participation for participants: Registration Package includes transportation ( from\to airport, from\to conference venue), simultaneous translation from Ukrainian or Russian to English language , certificate of participation (English language) ,participation in scientific sessions, conference materials, visit to the exhibition and 10-30% discount for accomodation اقرأ المزيد

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العلاج بالخلايا الجذعية في أوكرانيا

Пример тестовых заданий для оформления сертификата GCP в 2021 году

Пример тестовых заданий для оформления сертификата GCP в 2021 году 1) Обязанностью представителя спонсора является : a) извещение главного исследователя в письменной форме о предстоящем аудите; b) извещение всех исследователей в письменной форме о предстоящем аудите. 2) Дата и время проведения аудита должны быть согласованы не менее чем за: a) اقرأ المزيد

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Positive Outcomes of Stem Cell Therapy for Autism: Biopathological, Biochemical, and Cellular Mechanisms

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by impairments in social communication, repetitive behaviors, and restricted interests. Although the exact etiology remains unclear, research points to a combination of genetic, environmental, immunological, and neuroinflammatory factors. Recent clinical and experimental studies have highlighted the therapeutic potential of stem اقرأ المزيد

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专家视角：静脉注射胚胎干细胞治疗半月板软骨再生的潜力

专家视角：静脉注射胚胎干细胞治疗半月板软骨再生的潜力 半月板损伤和退变是导致膝关节功能障碍和疼痛的主要原因之一，尤其常见于运动员和中老年人群。半月板是膝关节内的一种纤维软骨结构，在负重分配、冲击吸收、关节稳定性和润滑中起关键作用。لكن，由于半月板内三分之二区域血供极差，其自身的修复能力极为有限。 半月板损伤的病因与发病机制 半月板损伤主要分为以下两类： 其发病机制包括： 上述机制导致半月板力学性能下降，并加速关节退化。 胚胎干细胞静脉注射对半月板再生的作用机制 胚胎干细胞（ESC）具有多能性和高度再生能力，代表了前沿的再生医学治疗方案。经静脉注射后，ESC主要通过旁分泌信号、免疫调节、向损伤区域归巢及营养支持来发挥治疗作用，而非单纯依赖细胞移植。 其关键作用机制如下： 1. 抗炎作用 ESC通过分泌抗炎因子（如IL-10、TGF-β）并抑制促炎因子（如IL-1β、TNF-α），降低局部和全身炎症，延缓基质降解。 2. 归巢到损伤区域 ESC通过趋化因子通路（如SDF-1/CXCR4轴）迁移至受损的半月板部位，释放生长因子并激活局部修复机制。 3. 促进基质修复与细胞增殖 ESC促进胶原蛋白I/II、聚集蛋白（Aggrecan）、润滑素等关键ECM成分的合成，并刺激纤维软骨细胞的增殖，抑制细胞凋亡。 4. 促进血管生成与供血改善 虽然半月板内侧无血管，但ESC可通过分泌VEGF、血管生成素等促进周边血管新生，提升营养供应和修复能力。 5. 免疫调节与抗纤维化 ESC通过抑制TGF-β1相关的纤维化信号，降低α-SMA和III型胶原表达，从而防止病理性组织重塑，保留半月板生物力学性能。 治疗后的临床效果与预期结果 虽然临床应用仍在早期阶段，但已有研究与观察表明，ESC静脉治疗后可见如下效果： 结论 静脉注射胚胎干细胞为半月板损伤的治疗提供了一种非侵入性、具有再生潜力的新思路。它不仅针对症状，更从根源上干预病理过程，如炎症、基质破坏和细胞凋亡等，从而实现组织再生与功能恢复。未来通过更多临床试验验证其安全性与有效性后，ESC疗法有望成为半月板损伤治疗的新标准。

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العلاج بالخلايا الجذعية في أوكرانيا

الخلايا الجذعية. Law for transplantation of organs or tissues

الخلايا الجذعية. Law for transplantation of organs or tissues Drafting of contracts that provide for the purchase and sale of organs or other anatomical material rights, except for bone marrow, are prohibited.   (Article 18. The ban on trade in organs and other anatomical material rights Act of 1999.07.16, “about اقرأ المزيد

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Immunoregulatory effects of treatment with mesenchymal stem cells on T-cell activity in cirrhosis

Mesenchymal stem cell (ماجستير) therapy’s immunomodulatory impact on T-cell activity in cirrhosis is analyzed. This article explores how MSC treatment modifies T-cell responses, potentially offering novel therapeutic strategies for managing cirrhosis-related immune dysfunction. {محتوى} reveals key findings.

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Inflammatory cytokine suppression by treatment with mesenchymal stem cells in fibrotic liver

Mesenchymal stem cell (ماجستير) therapy shows promise in treating fibrotic liver disease. This article analyzes MSC’s efficacy in suppressing inflammatory cytokines, a key driver of liver fibrosis progression. Explore the mechanisms and potential therapeutic benefits of MSC treatment. {محتوى}

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Treatment with mesenchymal stem cells reverses lipid accumulation in steatotic cirrhotic liver

Mesenchymal stem cell (ماجستير) therapy shows promise in reversing liver fat accumulation (steatosis) in cirrhosis. Our analysis reveals MSC treatment significantly reduces hepatic lipid content, offering a potential novel therapeutic approach for this challenging condition. {محتوى} explores the mechanisms and clinical implications.

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Treatment with mesenchymal stem cells normalizes hepatic nitric oxide signaling

Mesenchymal stem cell (ماجستير) therapy shows promise in normalizing hepatic nitric oxide (NO) signaling. Our analysis reveals how MSC treatment restores disrupted NO pathways, offering potential new avenues for liver disease treatment. Explore the mechanisms and therapeutic implications. #MSC #LiverDisease #NitricOxide

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