癫痫干细胞疗法 .
癫痫作为最常见的神经系统疾病之一，影响超过 50 全球 100 万人中低收入国家的患病率较高. 神经细胞损伤或丢失后神经元过度放电导致反复发作. One of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (TLE) which results from hippocampal sclerosis. Nowadays, similar to other diseases, epilepsy also is a candidate for treatment with different types of stem cells.
Various stem cell types were used for treatment of epilepsy in basic and experimental researches.
Two 干细胞治疗 has been shown efficacious in treating experimental models of neurological disorders, including Parkinson’s disease, and neuropsychiatric diseases, such as depression
Major roles of 干细胞疗法 in epilepsy are prophylaxis against chronic epilepsy and amelioration cognitive function after the occurrence of TLE.
诱导多能干细胞 (诱导多能干细胞)
Some epilepsies are caused because of a genetic mutation or change in neurons. 例如, Dravet syndrome is a devastating form of childhood epilepsy caused by a mutation in a specific sodium channel.
Scientists have found a way to take stem cells from people with Dravet syndrome and program them to become any type of cell in the body. These new cell types are called pluripotent stem cells. These new cells can be made into neurons.
Although much more research needs to be done, 干细胞疗法 is an attractive and promising treatment for epilepsy.
