6. 克罗恩病
Intravenous infusion of autologous MSCs has demonstrated significant efficacy in managing Crohn’s disease by reducing abdominal pain, 改善肠道功能, 并减少炎症. 间充质干细胞通过抑制促炎细胞因子调节免疫反应, 增强调节性 T 细胞活性, 并促进粘膜愈合. The paracrine signaling of MSCs stimulates epithelial regeneration and reduces the inflammatory response in the gut. These cells migrate to the inflamed intestinal tissues, offering long-lasting improvements in disease control and quality of life.
7. 溃疡性结肠炎
MSC therapy provides relief for patients with ulcerative colitis by improving bowel habits, reducing rectal bleeding, and decreasing overall intestinal inflammation. The mechanisms behind MSC effectiveness include immune system modulation by decreasing Th1/Th17 cytokine production, enhancing the regenerative capacity of the intestinal epithelium, 并促进组织修复. MSCs home to inflamed colon areas via circulating inflammatory signals, effectively reducing chronic inflammation and promoting mucosal healing.
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