Dernière mise à jour: Août 17, 2026
- Thérapie génique d'amélioration cognitive du SNC et thérapie génique double – Thérapie génique à la follistatine et à la télomérase
2) Dementia Intranasal Gene Therapy
Klotho Links To Articles
The Putative Role of the Antiageing Protein Klotho in Cardiovascular and Renal Disease
https://www.hindawi.com/journals/ijhy/2012/757469/
Klotho at the Edge of Alzheimer’s Disease and Senile Depression
https://www.ncbi.nlm.nih.gov/pubmed/29978424
Is Klotho the Key to Treating Alzheimer’s and Other Diseases of Aging?
https://www.biospace.com/article/is-klotho-the-key-to-treating-alzheimer-s-and-other-diseases-of-aging-/
One Day There May Be a Drug to Turbocharge the Brain.
https://www.nytimes.com/2019/04/02/health/klotho-brain-enhancement-dementia-alzheimers.html
Follistatin Links to Articles
“Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy Patricio V. Sepulveda https://www.nature.com/articles/srep17535 WEB 2015
Abellan van Kan, G. “Epidemiology and consequences of sarcopenia.” The journal of nutrition, santé & vieillissement 13.8 (2009): 708-712.
Amthor, Helge, et autres. “Lack of myostatin results in excessive muscle growth but impaired force generation.” Proceedings of the National Academy of Sciences 104.6 (2007): 1835-1840.
Amthor, Helge, and Willem MH Hoogaars. “Interference with myostatin/ActRIIB signaling as a therapeutic strategy for Duchenne muscular dystrophy.” Current gene therapy 12.3 (2012): 245-259.
Anker SD, Negassa A, Coats AJ, et autres. Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study. Lancet 2003;361:1077–83.
Argiles JM, Anker SD, Evans WJ, et autres. Consensus on cachexia definitions. J Am Med Dir Assoc 2010;11:229–30
Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. Myostatin
promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting
their differentiation into myofibroblasts. J Endocrinol 2008;196:235–49
Barns, Mitchell, et autres. “Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.” The international journal of biochemistry & biologie cellulaire 53 (2014): 174-185.
Bartke, Andrzej. “Growth hormone and aging: a challenging controversy.” Clin Interv Aging 3.4 (2008): 659-665.
Becker, Clemens, et autres. “Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial.” The lancet Diabetes & endocrinology 3.12 (2015): 948-957.
Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA. Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia. Biochem Biophys Res Commun. 2010;391:1548–54.
Berardi, Emanuele, et autres. “Molecular and cell-based therapies for muscle degenerations: a road under construction.” Frontiers in physiology 5 (2014): 119.
Examen de cas scientifiques
Souhaitez-vous savoir si les programmes cliniques actuels, développements récents en recherche, ou des approches émergentes peuvent être adapté à votre situation individuelle?
Partagez votre question avec notre équipe de recherche scientifique et recevez informations axées sur les domaines de recherche en cours qui peuvent être pertinent pour votre cas.
- Examen des informations que vous fournissez
- Informations pertinentes sur la recherche et les programmes cliniques
- Une réponse claire et adaptée à votre situation
Aucune obligation. Votre question sera examinée de manière confidentielle.
Informations pédagogiques et de recherche uniquement. Ce service ne constituer un avis médical, diagnostic, ordonnance, ou un personnalisé recommandation de traitement.
