干细胞治疗 用于勃起功能障碍: A Step towards a Future Treatment
Abstract
Background: The improvement of absent or partial response in the medical treatment of erectile dysfunction (急诊科) has led to the development of minimally invasive new treatment modalities in the field of regenerative medicine. Methods: A literature review on 干细胞疗法 for the treatment of ED was performed. We searched for the terms “erectile dysfunction” and “stem cell therapy” in PubMed and Clinicaltrials.gov. Literature searching was conducted in English and included articles from 2010 到 2022. Results: New treatment modalities for ED involving 干细胞疗法 are not only conceived with a curative intent but also aim to avoid unnecessary adverse effects. Several sources of stem cells have been described, each with unique characteristics and potential applications, and different delivery methods have been explored. A limited number of interventional studies over the past recent years have provided evidence of a safety profile in their use and promising results for the treatment of ED, although there are not enough studies to generate an appropriate protocol, dose or cell lineage, or to determine a mechanism of action. Conclusions: 干细胞治疗 is a novel treatment for ED with potential future applications. 然而, most urological societies agree that further research is required to conclusively prove its potential benefit.
关键词: erectile dysfunction (急诊科), 干细胞疗法, 间充质干细胞 (MSC), 骨髓干细胞 (BMSC), adipose-derived stem cells, intracavernous injection (ICI)
