Last updated: August 17, 2026
FREE RADICAL PROCESSES IN THE BLOOD OF PATIENTS WITH
EISENMENGER’S SYNDROME
Yu.I. Gubskiy, K.M. Amosova, L.F. Konoplyova, Ye.M. Zadorin
NATIONAL MEDICAL UNIVERSITY BY O.O. BOHOMOLETS
Summary
Study of lipid peroxidation processes and general antioxidizing activity of plasma and blood erythrocytes of
the patients with congenital heart disease (Eisenmenger’s Syndrome) were carried out for the first time. It was
shown, that in the patients with Eisenmenger’s Syndrome with intimate NYHA insufficiency of I-II class as well as
III-IV classes the lipid peroxidation processes in plasma and blood erythrocytes are considerably activated. Thus,
general antioxidizing activity of blood plasma also is reduced. The change of free-radical processes, probably,
is connected with the expressed damage of lung vessels, and, in turn, can result in deterioration of vessel
endothelium status and organs distrophy, which develop under the conditions of heart insufficiency.
KEY WORDS: Eisenmenger’s Syndrome, lipid peroxidation, general antioxidizing activity.
Scientific Case Review
Would you like to understand whether current clinical programs, recent research developments, or emerging approaches may be relevant to your individual situation?
Share your question with our scientific research team and receive information focused on the areas of current research that may be relevant to your case.
- Review of the information you provide
- Relevant research and clinical program information
- A clear response focused on your situation
No obligation. Your question will be reviewed confidentially.
Educational and research information only. This service does not constitute medical advice, diagnosis, prescription, or a personalized treatment recommendation.
