Stem Cell Therapy for Cholestasis: Una descripción general
Cholestasis, a condition characterized by impaired bile flow, can lead to liver damage and fibrosis. Las opciones de tratamiento actuales son limitadas y a menudo ineficaces.. Terapia con células madre has emerged as a promising approach for cholestasis treatment, offering the potential for tissue regeneration and functional restoration.
Current Challenges in Cholestasis Treatment
Conventional cholestasis treatments, such as ursodeoxycholic acid and cholestyramine, provide symptomatic relief but do not address the underlying cause. Liver transplantation is the only curative option for end-stage cholestasis, but it is limited by donor availability and the risk of complications.
Stem Cells as a Potential Therapeutic Option
Las células madre poseen la capacidad de autorrenovarse y diferenciarse en varios tipos de células.. Their regenerative potential makes them an attractive therapeutic option for cholestasis, where damaged liver cells can be replaced or repaired. Las células madre pueden derivarse de diversas fuentes., incluyendo la médula ósea, tejido adiposo, y sangre del cordón umbilical.
Types of Stem Cells for Cholestasis Treatment
Different types of stem cells have been investigated for cholestasis treatment. Células madre mesenquimales (MSC) are multipotent cells that can differentiate into various cell types, incluidas las células del hígado. Células madre hepáticas (HSC) are liver-specific stem cells that can regenerate liver tissue. Células madre embrionarias (ESC) Son células pluripotentes que pueden diferenciarse en cualquier tipo de célula del cuerpo..
