العلاج بالخلايا الجذعية للصرع .
الصرع باعتباره واحدا من الاضطرابات العصبية الأكثر شيوعا يؤثر على أكثر من 50 مليون شخص في جميع أنحاء العالم مع معدل انتشار أعلى في البلدان المنخفضة الدخل. تؤدي التفريغات الكهربائية المفرطة في الخلايا العصبية بعد تلف الخلايا العصبية أو فقدانها إلى حدوث نوبات متكررة. One of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (TLE) which results from hippocampal sclerosis. Nowadays, similar to other diseases, epilepsy also is a candidate for treatment with different types of stem cells.
Various stem cell types were used for treatment of epilepsy in basic and experimental researches.
Two العلاج بالخلايا الجذعية has been shown efficacious in treating experimental models of neurological disorders, including Parkinson’s disease, and neuropsychiatric diseases, such as depression
Major roles of العلاج بالخلايا الجذعية in epilepsy are prophylaxis against chronic epilepsy and amelioration cognitive function after the occurrence of TLE.
تتضمن الخلايا الجذعية المحفزة (iPSCs)
Some epilepsies are caused because of a genetic mutation or change in neurons. على سبيل المثال, Dravet syndrome is a devastating form of childhood epilepsy caused by a mutation in a specific sodium channel.
Scientists have found a way to take stem cells from people with Dravet syndrome and program them to become any type of cell in the body. These new cell types are called الخلايا الجذعية متعددة القدرات. These new cells can be made into neurons.
Although much more research needs to be done, العلاج بالخلايا الجذعية is an attractive and promising treatment for epilepsy.
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