干细胞

can self-renew and produce different cell types, 从而提供再生缺失组织和治疗疾病的新策略. 在牙科领域, 成体间充质干细胞/基质细胞 (间充质干细胞) 已在多种口腔和颌面部组织中发现, which suggests that the oral tissues are a rich source of stem cells, and oral stem and mucosal cells are expected to provide an ideal source for genetically reprogrammed cells such as induced pluripotent stem (iPS) 细胞.

此外, oral tissues are expected to be not only a source but

also a therapeutic target for stem cells, as stem cell and tissue engineering therapies in dentistry continue to attract increasing clinical interest. Part I of this review outlines various types of intra- and extra-oral tissue-derived stem cells with regard to clinical availability and applications in dentistry.

此外, appropriate sources of stem cells for regenerative dentistry are discussed with regard to differentiation capacity, accessibility and possible immunomodulatory properties.