can be used to treat a variety of autoimmune disorders including:
chronic inflammatory demyelinating polyneuropathy.
Lambert-Eaton myasthenic syndrome.
Plasmapheresis– is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation. It is thus an extracorporeal therapy (a medical procedure performed outside the body).
Three general types of plasmapheresis can be distinguished:
Autologuous, removing blood plasma, treating it in some way, and returning it to the same person, as a therapy.
Exchange, removing blood plasma and exchanging it with blood products to be donated to the recipient. This type is called plasma exchange (PE, PLEX, or PEX) or plasma exchange therapy (PET). The removed plasma is discarded and the patient receives replacement donor plasma, albumin, or a combination of albumin and saline (usually 70% albumin and 30% saline).
Donation, removing blood plasma, separating its components, and returning some of them to the same person while holding out others to become blood products donated by the donor. In such a plasma donation procedure, blood is removed from the body, blood cells and plasma are separated, and the blood cells are returned while the plasma is collected and frozen to preserve it for eventual use as fresh frozen plasma or as an ingredient in the manufacture of a variety of medications.
Plasmapheresis of the autologuous and exchange types is used to treat a variety of disorders, including those of the immune system, such as Goodpasture’s syndrome, Guillain–Barré syndrome, lupus, myasthenia gravis,and thrombotic thrombocytopenic purpura.
A plasma exchange can help to alleviate symptoms of the conditions above by removing harmful substances from the blood.
If a person has an autoimmune condition, a plasma exchange may also prevent the body from producing more harmful antibodies.
The procedure is usually one element of a treatment plan, which may include chemotherapy. Repeated plasma exchanges may be necessary.
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Contact Dr. Eugene Zadorin