1. CNS Cogntive Enhancement Gene Therapy and Dual Gene Therapy – Follistatin and Telomerase Gene Therapy

2) Dementia Intranasal Gene Therapy

Klotho Links To Articles

The Putative Role of the Antiageing Protein Klotho in Cardiovascular and Renal Disease

Klotho at the Edge of Alzheimer’s Disease and Senile Depression

Is Klotho the Key to Treating Alzheimer’s and Other Diseases of Aging?

One Day There May Be a Drug to Turbocharge the Brain.

Follistatin Links to Articles

“Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy Patricio V. Sepulveda https://www.nature.com/articles/srep17535 WEB 2015

Abellan van Kan, G. “Epidemiology and consequences of sarcopenia.” The journal of nutrition, health & aging 13.8 (2009): 708-712.

Amthor, Helge, et al. “Lack of myostatin results in excessive muscle growth but impaired force generation.” Proceedings of the National Academy of Sciences 104.6 (2007): 1835-1840.

Amthor, Helge, and Willem MH Hoogaars. “Interference with myostatin/ActRIIB signaling as a therapeutic strategy for Duchenne muscular dystrophy.” Current gene therapy 12.3 (2012): 245-259.

Anker SD, Negassa A, Coats AJ, et al. Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study. Lancet 2003;361:1077–83.

Argiles JM, Anker SD, Evans WJ, et al. Consensus on cachexia definitions. J Am Med Dir Assoc 2010;11:229–30

Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. Myostatin
promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting
their differentiation into myofibroblasts. J Endocrinol 2008;196:235–49

Barns, Mitchell, et al. “Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.” The international journal of biochemistry & cell biology 53 (2014): 174-185.

Bartke, Andrzej. “Growth hormone and aging: a challenging controversy.” Clin Interv Aging 3.4 (2008): 659-665.

Becker, Clemens, et al. “Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial.” The lancet Diabetes & endocrinology 3.12 (2015): 948-957.

Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA. Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia. Biochem Biophys Res Commun. 2010;391:1548–54.

Berardi, Emanuele, et al. “Molecular and cell-based therapies for muscle degenerations: a road under construction.” Frontiers in physiology 5 (2014): 119.

Categories: Stem Cells therapy


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stem cell therapy