Osteoartritli Hastalarda hUC Mezenkimal Kök Hücre（19#iSCLife®-OA） Tedavisinin Güvenliği/Etkililiği
This is a random, açık etiketli, ve paralel kontrollü deney. Tüm hastalar seçilir ve onay formlarını imzalar, sonra ikiye bölündü 3 gruplar. Doktorlar hastanın temel bilgilerini toplar. All patients receive laboratory and image examination as baseline. Daha sonra, they will give cell treatment based on the clinical protocol. Doctors have follow-up visit on 2 haftalar, 1, 2, 3, 6, Ve 12 months after treatment, and do safety and efficacy evaluation.
Safety evaluation. Researcher collect all examination data of patients and compare with each groups. The safety tests including blood routine, urine routine, hepatorenal function, C reactive protein, erythrocyte sedimentation rate, and tumor marker, vesaire.
Efficacy evaluation. Based on Lysholm, the international knee documentation committee (IKDC) knee evaluation form, and Visual Analogue Scale/Score (VAS) to examine the change/improvement of knee joint function. By Magnetic Resonance Imaging (MR) examination, grade patients with Kellgren-Lawrence Grading Scale, Assessment of Preoperative Cartilage Defect Severity (AMADEUS), and observe the change/improvement of patient.
