Son güncelleme: Ağustos 17, 2026
- CNS Bilişsel Güçlendirme Gen Terapisi ve İkili Gen Terapisi – Follistatin ve Telomeraz Gen Terapisi
2) Dementia Intranasal Gene Therapy
Klotho Links To Articles
The Putative Role of the Antiageing Protein Klotho in Cardiovascular and Renal Disease
https://www.hindawi.com/journals/ijhy/2012/757469/
Klotho at the Edge of Alzheimer’s Disease and Senile Depression
https://www.ncbi.nlm.nih.gov/pubmed/29978424
Is Klotho the Key to Treating Alzheimer’s and Other Diseases of Aging?
https://www.biospace.com/article/is-klotho-the-key-to-treating-alzheimer-s-and-other-diseases-of-aging-/
One Day There May Be a Drug to Turbocharge the Brain.
https://www.nytimes.com/2019/04/02/health/klotho-brain-enhancement-dementia-alzheimers.html
Follistatin Links to Articles
“Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy Patricio V. Sepulveda https://www.nature.com/articles/srep17535 WEB 2015
Abellan van Kan, G. “Epidemiology and consequences of sarcopenia.” The journal of nutrition, sağlık & yaşlanma 13.8 (2009): 708-712.
Amthor, Helge, ve diğerleri. “Lack of myostatin results in excessive muscle growth but impaired force generation.” Proceedings of the National Academy of Sciences 104.6 (2007): 1835-1840.
Amthor, Helge, and Willem MH Hoogaars. “Interference with myostatin/ActRIIB signaling as a therapeutic strategy for Duchenne muscular dystrophy.” Current gene therapy 12.3 (2012): 245-259.
Anker SD, Negassa A, Coats AJ, ve diğerleri. Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study. Lancet 2003;361:1077–83.
Argiles JM, Anker SD, Evans WJ, ve diğerleri. Consensus on cachexia definitions. J Am Med Dir Assoc 2010;11:229–30
Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. Myostatin
promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting
their differentiation into myofibroblasts. J Endocrinol 2008;196:235–49
Barns, Mitchell, ve diğerleri. “Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.” The international journal of biochemistry & cell biology 53 (2014): 174-185.
Bartke, Andrzej. “Growth hormone and aging: a challenging controversy.” Clin Interv Aging 3.4 (2008): 659-665.
Becker, Clemens, ve diğerleri. “Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial.” The lancet Diabetes & endocrinology 3.12 (2015): 948-957.
Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA. Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia. Biochem Biophys Res Commun. 2010;391:1548–54.
Berardi, Emanuele, ve diğerleri. “Molecular and cell-based therapies for muscle degenerations: a road under construction.” Frontiers in physiology 5 (2014): 119.
Bilimsel Vaka İncelemesi
Mevcut klinik programların olup olmadığını anlamak ister misiniz?, son araştırma gelişmeleri, veya ortaya çıkan yaklaşımlar olabilir kişisel durumunuzla alakalı?
Sorunuzu bilimsel araştırma ekibimizle paylaşın ve olabilecek güncel araştırma alanlarına odaklanan bilgiler sizin durumunuzla alakalı.
- Sağladığınız bilgilerin gözden geçirilmesi
- İlgili araştırma ve klinik program bilgileri
- Durumunuza odaklanmış net bir yanıt
Hiçbir yükümlülük yok. Sorunuz gizli olarak incelenecektir.
Yalnızca eğitim ve araştırma bilgileri. Bu hizmet tıbbi tavsiye teşkil eder, teşhis, reçete, veya kişiselleştirilmiş tedavi önerisi.
