Stem cell therapy holds promising potential for treating metabolic liver diseases, offering regenerative and immunomodulatory capabilities. Research explores the use of various stem cell types, incluindo células-tronco mesenquimais, liver progenitor cells, and induced pluripotent stem cells, to restore liver function, reduzir a inflamação, and promote tissue regeneration. The understanding of stem cell biology and the development of novel delivery strategies continue to advance the field, paving the way for personalized and effective treatments for metabolic liver diseases.